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Some of the assumptions of traditional parametric statistical tests are sensitive to small sample sizes, and the use of non-parametric statistical tests, as was employed here, can overcome these assumptions with increased robustness to skewness and outliers

Edibles take longer to kick in but provide a stronger, full-body high due to the liver converting THC into a more potent form, resulting in longer-lasting effects

The leaves are tied into bundles called hands of 10 or 15 leaves each

However, these extraction methods are likely inclusive of the wider Piper methysticum secondary metabolome (in additional to the kavalactones) that is likely to contribute both to efficacy and side effect limitation