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On this basis and given that the average pack-years in this sample's current and ex-smokers was 29.7, it took roughly 25 years without smoking for differences in cortical thickness to no longer be observed between ex-smokers and those that never smoked

International data, although more limited, suggest similar trends in other high-income settings 6

Nicotine, though optional, is a common part for users seeking a nicotine hit without the harmful byproducts associated with traditional tobacco combustion

The Lancet Respiratory Medicine, 9 (11), 12411254

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