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L-Carnitine can interact with thyroid medications, affecting thyroid function

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Long-term safety data is absent

Funding This work was supported by the Spanish Ministry of Science, Innovation and Universities through grant RTI2018-094629-B-I00 to W.L., and Fundao para a Cincia e TecnologiaFCT (PTDC/MED-ONC/4167/2020) and Algarve Biomedical Center (ABC) to B.I.F

"Nonetheless, we believe it is a class effect." The researchers measured the rate at which patients developed four different serious stomach conditions while taking semaglutide, liraglutide and bupropion-naltrexone, which are stomach paralysis, pancreatitis, bowel obstruction and biliary disease, a group of conditions affecting the gall bladder

In the study, 74 patients between the ages of 43 and 53 diagnosed with NASH received either 2 grams of L-carnitine per day (1 gram tablet after breakfast and one after dinner = 36 patients) or placebo (38 patients) for 24 weeks