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Indeed, when a wave of product liability suits brought by dying smokers or their families hit the industry in the 1980s, industry lawyers could gloat that no tobacco company has ever paid one penny in damages to a plaintiff

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Other common socio-demographic variables including age and profession are not significant to the knowledge about the effect of tobacco smoking, passive tobacco smoking, and smokeless tobacco use

Lopez-Moya, F

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Therefore, it is significant to distinguish (somewhat artificially) the pathways dependent on exposure time courses and the subsequent temporal significance of biological responses