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618 This mitochondrial remodeling supports a proinflammatory state via ROS signaling

Invasion by oral microbiota can amplify inflammatory responses

Primary clinical applications include skin quality, hair density, and wound and post-procedure recovery

Screening may be warranted in patients with one or more risk factors, such as gastric or small intestine resections, inflammatory bowel disease, use of metformin for more than four months, use of proton pump inhibitors or histamine H 2 blockers for more than 12 months, vegans or strict vegetarians, and adults older than 75 years

Monitoring and dosage adjustments may be needed.

systematic reviews indicate that short-term oral contraceptive use does not significantly alter the gut microbiota in PCOS patients (109)