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In our study we show that (1) current smoking rates among American adults over the last five decades have fallen because persons over the age of ~ 27 had a lower probability of cigarette use, and (2) the decline in prevalence of smoking from 1971 to 2020 has not been equal among birth cohorts

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Considering the interaction effects of smoking and drinking, we further explore the interaction effect on hypertension by establishing a new model containing the tobacco-alcohol interaction term in Supplementary Table 2

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