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More research is needed on the health effects of synthetic nicotine

PM's comparison of secondhand smoke with diesel exhaust (also conducted at INBIFO) had 99 rats of each gender in each exposure group, exposed the rats for 24 mo (730 d) with a 6-mo (183 d) follow-up [101],[102]

They could include: Temporary bursts of energy and talkativeness, followed by listlessness and comedowns Dilated pupils Extreme mood swings Weight loss Difficulty sleeping Paranoid behaviour, anxiety Money problems Secretive behaviour Specific signs of freebasing could also include: Finding glass pipes Respiratory problems such as coughs, wheezing and difficulty breathing

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Schrek, R., Baker, L