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The FDA has denied permission to market many non-tobacco and non-menthol flavored e-cigarette products, however, many of those denials are currently under judicial or supervisory review

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The Center for Disease control estimates that nearly 480,000 premature deaths can be attributed to tobacco abuse in the US every year

Based on these premises, smokers who quit may be at increased risk of developing DIH and thus may require dose adjustment to avoid liver damage

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