(132), demonstrated that gut microbiota metabolites derived from dietary polyphenols (e.g., quercetin, proanthocyanidins, and kaempferol), such as 3,4-dihydroxyphenylacetic acid (3,4-DHPAA) and 4-hydroxyphenylacetic acid (4-HPAA), can counteract the immunosuppressive effects of heme on macrophages
Consider the following facts to determine which one is more effective
Dasari S, Njiki S, Mbemi A, Yedjou CG, Tchounwou PB (2022) Pharmacological Effects of Cisplatin Combination with Natural products in cancer chemotherapy
However, its intrinsic physicochemical drawbacks, including poor aqueous solubility and high susceptibility to oxidative degradation, pose major challenges for its biomedical application [302]
Sebagai contoh, dosis vitamin C yang terlalu tinggi bisa saja menyebabkan efek samping berupa: Mual Muntah Nyeri perut Diare Sakit kepala Gangguan tidur Masalah di ginjal Efek samping glutation yang berlebihan dapat berupa gangguan pencernaan, bahkan masalah di organ hati
Muscle maintenance & performance