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BPC-157: 250-500 mcg once or twice daily for 6-8 week cycles Cryotherapy: 2-3 sessions per week (whole-body or local application) Schedule cryotherapy on high-activity or high-pain days Take 4-8 weeks off between BPC-157 cycles Approach for acute worsening of chronic conditions

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Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease