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Action is needed to remove illegal e-cigarettes that risk furthering nicotine addiction The premarket review process provides the FDA with an objective and systematic method to evaluate whether an e-cigarette product benefits public health and can be legally marketed in the United States

[14] In response, Robin Sommers, the CEO and majority owner of Santa Fe Natural Tobacco Company, stated that "Native Americans are not a target market for American Spirit", stating that the use of this imagery was due to the company's goal to bring tobacco usage more in line with a perceived "moderation" by Indigenous peoples in the 15th century and that proceeds from sales support Native communities

They may vary based on the number of cigarettes packed inside