Neutrophils and macrophages also release reactive oxygen species, pro-inflammatory cytokines, growth factors and MMPs, which propagate chronic inflammation, emphysema, and airway remodelling processes, such as EMT, fibroblast activation and airway smooth muscle proliferation ( Figure 3 )
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The risk of a newborn being admitted to intensive care was 13% higher for women who smoked one to two cigarettes a day during pregnancy and 29% higher for women who smoked 20 cigarettes or more a day, according to the research
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