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Acknowledgements The authors are grateful to Tanya McLaven, Deputy Librarian, University Hospital Leicester, UK for the comprehensive literature review, and Dr Neshantha Harishchandra, PhD, Senior Lecturer, Department of English and Linguistics, the University of Ruhuna for proofreading the manuscript of this article

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If the panel looks favorably upon IQOS, and FDA takes its recommendation (it usually does), the device would be the first tobacco product marketed under a modified risk claim in the US