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[52] Cannabinoids produce a marked depression of motor activity via activation of receptors of cannabinoid receptor type 1

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As in individuals who smoked 30 or more doses daily, RR was 1.75 and in those who smoked at least 50 years, while in people who had left smoking for more than 15 years, RR was similar to those who never smoked [87]

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(2023), 25% of adolescents in Europe begin to consume alcohol as early as the age of 13, and depending on region and gender, the prevalence of weekly alcohol consumption from adolescents is anywhere from 2%-33%