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E5 is located in the membrane of infected cells, where it binds to the epidermal growth factor receptor (EGFR), promoting its dimerization and activation, resulting in mitogenic signals to the nucleus, and thus stimulating cell proliferation [31]

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doi:10.1016/j.amepre.2005.04.013

These include: DPP-4 inhibitors also known as gliptins, these increase the amount of insulin that your pancreas makes and reduce the amount of stored glucose that is released from your liver

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