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Smoking cigarettes and bidis is known to double the risk of heart attacks

Comparing pairs of monozygotic female twins, full sisters, half sisters and female cousins selected on the basis of discordance for smoking, the research team hypothesised that the strength of the association between smoking and non-affective psychosis should decline with pairs of increasing genetic relationship

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[14] Action on Smoking and Health (ASH)

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So how do people know if they might have a high degree of dependence on nicotine