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Authors: Jens Neumann, Joo Aguiar Machado, Miriam Grtzen, Lena Geier The global obesity treatment market is expanding at an unprecedented pace, with sales of weight loss medications forecast to rise dramatically over the next decade

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A phase 2B clinical trial (HARMONY) revealed that efruxifermin, a bivalent Fc-FGF21 analog, improved hepatic inflammation and fibrosis over 24 weeks in patients with F2 or F3 fibrosis, with an acceptable safety profile, warranting further investigation in phase 3 trials (NCT04767529)

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