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Peptic ulcers are the most common cause of acute upper GI bleeding
EU product information explicitly warns that nausea, vomiting and diarrhoea may cause dehydration and advises precautions to avoid fluid depletion
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GLP-1 medications can be safely combined with other wellness treatments, including peptides like NAD+
Patient Selection Ideal patient No recent opioid use Interested in cutting back on alcohol use Wants medications to reduce cravings Positive screening on tools such as SASQ, AUDIT-C, AUDIT, or STAD Naloxone challenge [14] Prior to naltrexone initiation, a dose of 0.4 mg IV naloxone can be administered to ensure that naltrexone will not precipitate withdrawal when being taken, Efficacy A 2023 meta-analysis found oral naltrexone (50 mg/d) reduced the risk of returning to heavy drinking (defined often as 5 drinks for men/4 drinks for women), with a number needed to treat (NNT) of roughly 11 [15]
