As a result, the skin loses its luster and becomes bland
The binding of Pycnogenol constituents and the bioactive microbial metabolite 5-(3,4-dihydroxyphenyl)--valerolactone to human erythrocytes was determined in an in vitro setting ( In a clinical study with 33 patients suffering from severe osteoarthritis 16 patients were allocated to receive 200 mg Pycnogenol per day over 3 weeks before a scheduled knee arthroplasty surgery ( constituents and metabolites were quantified in serum (see section 4.1 Absorption into plasma/serum and concentration profiles), synovial fluid (see section 5.4 Distribution into synovial fluid) and blood cells (Table 2)
10.18632/oncotarget.17638 296 ZhangX.WangX.HuX.ChuX.LiX.HanF
Its often called the master antioxidant because it neutralizes free radicals and aids liver detoxification
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Aguilar, Autrup, et al., Use of rosemary extracts as a food additive - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food, EFSA Journal, vol