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Post-treatment, clinical parameters (gingival colour and consistency, plaque index, bleeding on probing [BoP], PPD, keratinised tissue width) and salivary inflammatory biomarkers (MMP-8, IL-6, IL-1, TIMP-1) were assessed at three time points: one month, six months, and one year

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Pharmacologically, caffeine enhances nicotine's dopamine effect the combined stimulant-dopamine reward is greater than either alone, making the pairing neurologically more satisfying

This allows vapers to reduce their nicotine consumption at a comfortable rate, all the while seeing the same improvements in bodily function associated with quitting smoking

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Because there are two stamp heads, the CSU-120D can be used for two different states without doing paper changes