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Extracellular release of galectin-8 was NDP52-dependent Galectin-8 binding to damaged vesicles triggers the recruitment of NDP52, which in turn interacts with LC3 via a non-canonical ATG8/LC3-interacting region (LIR) motif, leading to autophagy-mediated clearance of the damaged vesicles 15,25

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Stotland and Gottlieb 2015)