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References 1 BMC Medicine: Relationship of tobacco smoking to cause-specific mortality: contemporary estimates from Australia 2 The Sax Institutes 45 and Up Study: www.saxinstitute.org.au/solutions/45-and-up-study/

28 No Clear Counterfactual The FDA and applicants would need to consider plausible counterfactuals

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A review that obtained estimates for WPR gave an odds ratio of 15.03 (95% CI: 9.8722.8) for Taiwan

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