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NIDDK notes that these medications act on receptors in the brain in ways that help decrease appetite, reduce cravings, and signal fullness

According to FDA-approved prescribing information for semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound), food intake does not significantly affect the absorption or efficacy of these subcutaneous injections

For this RCT, we identified a conference abstract that similarly reported a positive effect of exenatide on weight reduction and BMI 146

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