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The key difference from cigarettes is that the speed of absorption depends heavily on the type of nicotine used : Freebase nicotine the form used in most older e-liquids and sub-ohm setups is absorbed more slowly than cigarette smoke nicotine

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They would usually burn them in a fire or smoke them from a pipe

doi:10.1177/0884533611399774

Written informed consent was obtained from all judges prior to participation in the study and before the initiation of any study procedures, including screening assessments

Amini S, Arsova B, Hanikenne M (2021) The molecular basis of zinc homeostasis in cereals