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In a systematic review of 40 studies investigating the role of secondhand smoke in allergic rhinitis 20 , tobacco smoke exposure was evaluated using a cotinine/creatinine ratio in only 1 study 21 , whereas all other studies used a questionnaire to evaluate tobacco smoke exposure

E.) American Chemical Society Monograph 182 Vol

1991 Chem

However, some important risk factors for CVD (such as tobacco smoking, poor diet, and lack of physical exercise), and environmental pollution have also been linked to an elevated risk of cardiovascular disease

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