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Cardiovascular features that were systematically explored included varicose veins, Raynauds phenomenon, acrocyanosis, livedo reticularis, capillary fragility, and recurrent epistaxis or gingival bleeding

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The subcellular localisation of these channels was not addressed, however

The primary objective of this review was to identify studies that offered valuable insights into the potential metabolic interactions between smoking, smoking cessation, and smoking cessation medications, with a focus on their impact on the pharmacokinetics and pharmacodynamics of antituberculous drugs