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Patients with a history of kidney stones should be vigilant about their fluid intake. Meeting the American Urological Associations recommended urine output of 2.5 liters per day generally requires around 96 ounces, or 3 liters, of daily fluid intake

References 1.Mueller SG

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However, clinical trials are not always powered or designed to capture lower-frequency or delayed-onset adverse effects such as telogen effluvium, which may emerge weeks to months after treatment initiation

For example, if you normally inject on Wednesday, moving to Friday or Monday is generally acceptable for occasional schedule changes