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As smokers either quit or shift to illicit and low-priced alternatives, legitimate cigarette sales decline, cutting packaging procurement for legal producers

Normalizing effects of EVP-6124, an alpha-7 nicotinic partial agonist, on event-related potentials and cognition: a proof of concept, randomized trial in patients with schizophrenia

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The drugs wide availability and misuse have fueled the opioid epidemic, leading to serious societal consequences such as overdose deaths, increased healthcare demands, and stricter legal control in many countries, like the United States, Canada, and Australia