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c-Jun N-Terminal kinases (JNKs) in myocardial and cerebral Ischemia/Reperfusion injury

Curr Opin Clin Nutr Metab Care 20(3):169174 Drori A, Shabat Y, Ben Ya'acov A, Danay O, Levanon D, Zolotarov L, Ilan Y (2016) Extracts from Lentinula edodes (Shiitake) edible mushrooms enriched with vitamin D exert an anti-inflammatory hepatoprotective effect

At 0.1 g/ml there were 230 % more than in the control In the live rat BPC-157 restored perfusion of the ischemic limb to 85 % in 14 days

Instead Grx2, a mitochondrial isoform, exhibits de-glutathionylation activity for peptides and proteins but with a catalytic activity 10-fold lower with respect to Grx1 ( S -glutathionylation can be catalyzed by glutathione- S -transferase P (GSTP)