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"Prohibition of Sale of Tobacco Products to Persons Younger Than 21 Years of Age"

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The study showed mechanistically that mtDNA released into the cytosol can bind to NLRP3, triggering its activation and the subsequent production of inflammatory cytokines like IL-1, contributing to inflammation in lung tissues (Nakahira et al., 2015) (Figure 2)

Smoking and cancer Tobacco smoking is the most common cause of cancer and is responsible for 1 in every 5 cancer deaths