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Therefore, the use of appropriate New Alternative Models (NAMs) is of great interest to obtain faster, more reliable, and cost-effective results, in experimental models that fulfill high ethical standards in alignment with the 3Rs Principle (Replacement, Reduction, and Refinement)

3.1.5 Trends in incidence of melanoma according to age: analysis of Global Cancer Observatory data It is difficult to compare trends in incidence of melanoma based on reports from the published literature due to the use of different populations for standardising age, as has been noted in the Panels annual assessments 20192021 [79,80,81]

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We talk about early intervention and prevention, but when its time to dole out the money, it always falls at the bottom of priorities, Gardner says