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The Epidemiological Survey of Substance Abuse (Epidemiologischer Suchtsurvey, ESA) yields population-representative data on the prevalence of legal and illegal substance use, hazardous forms of use, as well as substance-related disorders according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)

While the ultimate impacts of e-cigarettes and other novel non-combusted tobacco products remain to be seen, there is widespread agreement that it is the burning of tobacco, primarily in the form of cigarette smoking, with its 7000 chemicals, that is by far the deadliest method of consuming tobacco.

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In a study by Van et al., which targeted online EC shop customers, 84% of EC users reported that they had experienced improvements in their general health after switching to EC products [40]