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Nicotine has been shown to inhibit the accumulation of tetraethylammonium (a model substrate for OCTs) in a human embryonic kidney cell line (HEK-293), mediated by OCT1 with an IC50 of 63 M and by OCT2 with an IC50 of 50 M in vitro (Urakami et al., 1998)

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Examples of support people: Friends Family Partner Mums & Bubs group Local tobacco champion Community Controlled Health Service worker Your Midwife GP or Doctor Yarning with your Mob about your quit journey and why you are choosing to quit can help them to understand your reasons for quitting