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55 A manufacturer must submit a premarket tobacco product application (PMTA) and receive a PMTA marketing authorization order to legally market a new tobacco product that is not substantially equivalent to a predicate tobacco product or exempt from substantial equivalence

For many smokers, cigarettes are a part of their daily routinesomething they do on a coffee break, while driving, or to relieve stress

Occupational heat exposure was strongly associated with elevated sperm DNA fragmentation, supporting the evidence that thermal stress induces oxidative damage and chromatin instability in spermatozoa, the researchers explained

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