In the derived splenocytes, resveratrol (10, 30 M) reduced the induction of CD25+ cells, IL-2, IL-4, IL-13 and IFN- associated with inhibition of GATA-3 and T-bet, suggested to be achieved through inhibition of dendritic cell maturation via co-stimulatory molecule CD80 and CD86 expression, and consequential early T cell activation and differentiation by repression of cyclic adenosine monophosphate (cAMP) activation of bone marrow derived dendritic cells [184]
& Lutsenko, S
The role of bioisosterism in molecular modification and drug design: a review
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Gut microbiota changes in preeclampsia, abnormal placental growth and healthy pregnant women
In particular, its immune-modulating and skin-brightening effects have increased its popularity in health and wellness markets (Lu et al., 2021)