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While sub-chronic exposure to PG/nicotine promote nAChR7-dependent increased levels of different cytokines and chemokines in the bronchoalveolar lavage fluid (BALF) such as IL-1, IL-2, IL-9, interferon (IFN), granulocyte-macrophage colony-stimulating factor (GM-CSF), monocyte chemoattractant protein-1 (MCP-1/CCL2) and regulated on activation, normal T cell expressed and secreted (RANTES/CCL5), the enhanced levels of IL-1, IL-5 and TNF were nAChR7 independent

The CDC says that every day, about 2,100 adolescents ages 18 or younger become daily cigarette smokers

If youre a heavy smoker, your levels are likely in the range of 1,000 to 8,000 ng/mL (nanograms per milliliter)

Smoking rates are high across many countries, but we know from experience that this can change quickly

ECigarette Health Concerns

To be fair, I do smoke cigars and pipes so cigarettes to me can seem a bit bland