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One of the main effects of insulin on the adipose tissue and the skeletal muscle is to increase glucose uptake, which is mediated by the increase in vesicular trafficking of the glucose transporter-4 (GLUT4) from intracellular compartments to the plasma membrane, resulting in insulin-stimulated glucose uptake (ISGU) (87)

AUTHORS' CONTRIBUTIONS CMS, AA and MB: were responsible for study conception and design with input from BS and FC

In sum, young adults, who are also often exposed to extensive digital marketing of nicotine products [19, 20], are priority populations for early smoking cessation interventions and sociodemographic risk factors need to be considered in the design of these interventions

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He was not receiving any drug treatment after his release from the hospital, before he went to a methadone clinic daily