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CJC-1295 without DAC (5mg) is a 29-amino-acid peptide analog of growth hormone-releasing hormone (GHRH)

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According to Riccardo Perfetti and colleagues from Cedars-Sinai Medical Center, Division of Endocrinology in Los Angeles, California, continuous infusion of GLP-1 to both young and old rats demonstrated an up-regulation of pancreatic-duodenum homeobox-1 (PDX-1) expression in islets and total pancreas which is essential for pancreogenesis, pancreatic cell differentiation, and maturation

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Acknowledgements We are grateful to Tibor Pli and Andrs Dr from the Institute of Biophysics, HUN-REN Biological Research Centre for providing access to the spectrofluorometer Fluorolog 3 (Horiba Jobin Yvon) and to the Malvern Zetasizer Nano ZS device (Malvern Instruments)