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Notional prevalence ( P e ) is an artificial concept that may be quite different from the true prevalence, depending on how different the past experience of tobacco smoking in the population under study was from that in the volunteers of the CPS II study

This nonmonotonic temporal pattern is illustrated in Figure 3 , where ANA prevalence estimates are smaller for smokers than nonsmokers in all three time periods, but the difference is much greater in Period 2 than in Periods 1 and 3

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