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Our approach also focused on modulating host responses during the initial phase (2-weeks) of TB treatments, as this period is associated with high mortality in patients with TB meningitis, and thus an ideal time for intervention 12,32,37,38

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CRP level and APACHE II score showed a significant decrease in the LC group compared to the control group ( P 0.05), while D-dimer and ferritin in the LC group were significantly less than the control group on days 4-7 ( P 0.05)

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32-34 Acute toxicities arise from sudden exposures to substantial quantities of some metals (such as from occupational exposure to aluminum dust or breaking a mercury-containing thermometer) and typically affect multiple organ systems, commonly the gastrointestinal tract, cardiovascular system, nervous system, endocrine system, kidneys, hair, and nails

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