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IBS is a common functional gut disorder, affecting an estimated 1015% of adults (especially women), and is characterized by chronic abdominal pain and changes in bowel habits

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Herg and Jacobs appear in King Ottokar's Sceptre (page 38, last frame) as men to the left in red and green dress uniforms, and later in the same book, Herg, his wife Germaine, Jacobs, and Van Melkebeke appear (page 59, last frame) as a man on the right in a green uniform accompanying a woman in mauve, a monocled man on the right with black hair and breastplate, and a fair-haired man in evening wear on the left near the window

Amino acids V12 (putative oxyanion hole), F112 (active site architecture), N108 (flavonoid binding) and C13 (GSH stabilization) were fully randomized by site saturation mutagenesis (NNK codons), and the created Pt GSTF8 variants were tested for conversion of flavan-3,3,4-triol ( 4 ) to cyanidin ( 8 ), and for their GSH-transferase activity towards CDNB ( 5 ) as a control of catalytic competence