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10.1080/08982104.2016.1174943 156 SinghJ

Glutamate excitotoxicity is a major effector that causes oxidative stress in the CNS, and autoxidation of neurotransmitters can also generate reactive oxygen species such as the superoxide anion radical (O 2 - ) [14]

NL was supported by an AIRC fellowship

Pros : Precise temperature control, extended duration, can plug into multiple power sources Cons : Higher cost, requires charging infrastructure, bulkier than passive options Hybrid Approach: Combining Methods Savvy travelers use multiple cooling methods: USB cooler for primary storage during travel days FRIO wallet as backup for day excursions Hotel refrigerator for overnight storage Gel pack backup if power sources fail This redundancy ensures medication stays protected regardless of circumstances

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In children with ASD with gastrointestinal problems, implementation of a specific carbohydrate diet protocol has not been evaluated but is an intervention commonly used by many families without clinical guidance