To view or add a comment, sign in The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a Science study from earlier this year in mice
Dr Bradley Pentelute, professor of chemistry at MIT, who will present his team's results at the spring meeting of the American Chemical Society (ACS 2025) in San Diego, developed a technology to attach GLP-1 receptor agonists to IgGs within the body
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For example, a patient might start with phentermine for 12 weeks to kickstart weight loss and then transition to a long-term GLP-1 program for maintenance and further reduction