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Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis

Cordiner RLM, Mari A, Tura A, et al

Shen, G

The remaining TRIUMPH trials (TRIUMPH-2/-3/-4 and TRIUMPH-Outcomes) have not yet reported and remain anticipated through 20262028

The study used 120 minutes of moderate-intensity exercise per week

Lacking FDA approval and recent extensive peer-reviewed data, its use for anti-aging, bodybuilding, or other non-FDA approved purposes is not evidence-based and carries substantial risks, including reported hypersensitivity reactions and unknown long-term endocrine disruption [fda.gov], [mayoclinic.org]