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10.1016/j.physbeh.2010.12.006 61 DossatA
The therapeutic effects of central leptin gene therapy have been reported in insulin-deficient diabetes and in obesity animal models, such as ob/ob, diet-induced obese mice, insulin-deficient type 1 diabetes mice, and insulin-dependent diabetes animals (Akita mice) (Dube et al., 2004, 2006
Thus, loss of TSC2 increases cells size and overexpression of the protein decreases cells size
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Because stacking the two sets of GI effects may intensify symptoms or mask early signs of medication intolerance
NasteskaDHaradaNSuzukiKYamaneSHamasakiAJooEet al
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