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When NRF2 translocates to the nucleus, it binds antioxidant response elements (AREs) in the promoter regions of GST genes, upregulating their expression

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Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: role of ATGL, HSL, and AMPK

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Consuming more fiber-rich foods can also help, as fiber promotes healthy bowel movements

JAMA 2018;319:1580-91.ArticlePubMedPMC 85