Additionally, alcohol can damage the cells lining the stomach and intestines leading to deficiencies of both vitamin B6 and B12, leading to anemia, neuropathy, and cognitive issues
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Acetaldehyde induces cytotoxicity by disrupting mitochondrial function to cause oxidative stress in neural cells (Yan et al., 2022), while acrolein causes DNA damage and oxidative stress in non-neural cells (Hikisz and Jacenik, 2023) and is elevated in the brain of patients with neurodegenerative diseases (Liu et al., 2018
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FO, JS, and EA: Assisted in writing the section on cardiovascular diseases