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Since gene-environment-interaction has been implicated in the pathogenesis of COPD ( 2

"By clearly defining synthetic nicotine products as tobacco, we have enhanced the protection of public health and the effectiveness of tobacco regulation," an MOHW official said

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Furthermore, long-term CSE exposure significantly increased the expression of specific fission/fusion markers (Fis1, Mfn1, Mfn2, Drp1 and Opa1), oxidative phosphorylation (OXPHOS) proteins (Complex II, III and V), and oxidative stress (Mn-SOD) markers

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