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Still, ibuprofen is a drug, and it comes with risks like any other drug

Carcinoma 8 , 435450 (2021)

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The researchers describe any effect sertraline may have had as clinically irrelevant and conclude, it is unlikely that sertraline is effective for depression treatment in this patient population. The researchers find that participants taking sertraline reported higher rates of nausea, vomiting, and diarrhea