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We initiated MD simulations by heating each system in the NVT ensemble from 0 to 300 K for 50 ps using a Langevin thermostat with a coupling coefficient of 1.0/ps and a force constant of 2.0 kcal/mol2 on the complex

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We used a lens of appreciative inquiry, a strengths-based approach which values different world views to ensure that the experiences described by both practices were considered equally valid [30]